Current Management  of osteoporosis

Current

Management  of

osteoporosis

H.Delshad M.D

Endocrinologist

Research Institute for Endocrine Sciences

►The most common metabolic bone disease

►The most common cause of Fx. in older adults

►2 million fracture each year :

               • 300,000 hip Fx.

          • 547,000 Vert. Fx.

          • 135,000 Pelvic Fx.

          • 20%  end up in nursing homes

          • 20%  mortality within 1 year of fracture

          • 2/3  never return to pre-fracture functional level

♦ Despite a substantial burden of disease and the availability of treatments for osteoporosis, problems remain in identifying patients in whom treatment should be considered .

♦ Global strategies to improve BMD in the general population are untested.

♦ Screening and case-finding strategies using BMD testing are specific (they identify high-risk patients) but lack sensitivity (they miss many who will experience fractures) .

♦ Case finding can be enhanced by the consideration of clinical risk factors that provide information on fracture risk over and above that provided by BMD measurements .

♦ The FRAX^® tool integrates information on fracture risk from clinical risk factors with or without BMD, and can be used to improve the targeting of treatment to individuals at high fracture risk.